New York Psychiatric Institute

2 ARTICLES PUBLISHED IN JoVE

Biology

Dopamine Release at Individual Presynaptic Terminals Visualized with FFNs

Hui Zhang^1,2, Niko G. Gubernator^3,4, Minerva Yue¹, Roland G. W. Staal¹, Eugene V. Mosharov¹, Daniela Pereira¹, Vojtech Balsanek³, Paul A. Vadola³, Bipasha Mukherjee⁵, Robert H. Edwards⁵, David Sulzer^1,2,6, Dalibor Sames³

¹Departments of Neurology, Columbia University, ²Departments of Psychiatry and Pharmacology, Columbia University, ³Department of Chemistry, Columbia University, ⁴eMolecules, Inc., ⁵Departments of Neurology and Physiology, University of California School of Medicine, San Francisco, ⁶Division of Molecular Therapeutics, New York Psychiatric Institute

A new means to measure neurotransmission optically using fluorescent dopamine analogs.

Neuroscience

Piezo High Accuracy Surgical Osteal Removal (PHASOR): A Technique for Improved Cranial Window Surgery in Mice

Samuel D. Clark¹, Rachel Mikofsky^*1, Jacqueline Lawson^*1, David Sulzer¹

¹Departments of Psychiatry, Neurology, & Pharmacology, Columbia University Medical Campus

Piezoelectric surgery has led to improvements in human maxillofacial and dental surgery. We have developed a protocol to optimize piezoelectric surgery for cranial window surgery in mice.